Author: Cheryl Stratos
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Patient Notification Service
Register your email address to be notified when new melanoma clinical trials are posted to the database. http://www.centerwatch.com/clinical-trials/pns/
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Holidays Are Always Good, Specially When They Can Extend Your Life
Alternating Dosages of Vemurafenib Could Delay or Prevent Resistance, WOW! In a new study published today in Nature, researchers using a mouse model of melanoma were able to prevent resistance to vemurafenib by altering the dosing schedule from a continuous daily dose to an intermittent dose, suggesting a possible way to prolong the onset of resistance for melanoma…
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Holidays Are Always Good, Specially When They Can Extend Your Life
Alternating Dosages of Vemurafenib Could Delay or Prevent Resistance, WOW! In a new study published today in Nature, researchers using a mouse model of melanoma were able to prevent resistance to vemurafenib by altering the dosing schedule from a continuous daily dose to an intermittent dose, suggesting a possible way to prolong the onset of resistance for melanoma…
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Genotype-Selective Combination Therapies for Melanoma Identified by High-Throughput Drug Screening
Drug combinatorial screening was used to identify effective combinations for mutant BRAF melanomas, including those resistant to vemurafenib, and mutant RAS melanomas that are resistant to many therapies. http://cancerdiscovery.aacrjournals.org/content/early/2012/12/07/2159-8290.CD-12-0408.abstract
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Yale team identifies successful combination drug therapies for melanoma mutations
Really? They found that combining statins with drugs that inhibited cyclin-dependent protein kinase enzymes, which regulate and promote the cellular growth of cancer, produced a similar response with both RAS- and BRAF-mutated oncogenes. http://news.yale.edu/2012/12/13/yale-team-identifies-successful-combination-drug-therapies-melanoma-mutations
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Suppressed protein halted melanoma metastasis
This is amazing!! They have found that inhibiting a specific protein eliminated metastasis of melanoma in laboratory experiments, a finding that could lead to targeted therapies to stop metastasis in not only melanoma but, potentially, a broad range of cancers. WOW! We are getting close Read more http://www.oncologynurseadvisor.com/suppressed-protein-halted-melanoma-metastasis/article/271157/